hrp0086p2-p428 | Gonads & DSD P2 | ESPE2016

Hematocolpos Revealed by Non-cyclic Lower-back Pain in a Pre-menarcheal Girl

Ly Nathalie , Jaroussie Marianne , Kyheng Christele , De Filippo Gianpaolo , Levy-Zauberman Yael , Fernandez Herve , Duranteau Lise

Background: Hematocolpos is a rare condition in young girls that can be caused by imperforated hymen or vaginal agenesis. It is usually diagnosed at early puberty with cyclic abdominal pain and amenorrhoea. Menarche is usually observed two years after the start of puberty; sometimes pre-menarcheal bleeding can occur, ranging from isolated premature menarche to spotting in course of puberty. In case of imperforated hymen or vaginal anomaly, a pre-menarcheal uterine bleeding can...

hrp0086p1-p448 | Fat Metabolism and Obesity P1 | ESPE2016

Laparoscopic sleeve gastrectomy in adolescents with morbid and dynamic obesity. A controlled monocentric study.

Filippo Gianpaolo De , Pourcher Guillaume , Castell Anne Laure , Kyheng Christele , Bougneres Pierre

Background: Following years of dietary and lifestyle intervention (DLI) as the only therapeutic option, reports of bariatric surgery are emerging in adolescents with morbid obesity. We present herein preliminary results of our 4-yr sleeve gastrectomy study.Objectives and hypotheses: To compare the effects of laparoscopic sleeve gastrectomy (LSG) and intensive DLI in adolescents with morbid obesity (ie BMI >4 DS) and extremely active weight gain (i.e....

hrp0082p2-d1-531 | Puberty and Neuroendocrinology | ESPE2014

Very Low Estradiol Levels are Independent From Duration of Amenorrhea in Girls with Severe Anorexia Nervosa

Kyheng Christele , De Filippo Gianpaolo , Castell Anne-Laure , Flandrin Jennifer , Durin Julie , Delafoy Manon , Duranteau Lise

Background: Anorexia nervosa (AN) is a primary psychiatric disease, complicated by serious endocrine disturbances. Hypogonadotropic hypogonadism with primary or secondary amenorrhea is the most common endocrine repercussion of AN, with consequent estrogen deficiency and concerns about bone mineral density. Furthermore, establishing regular menstrual cycles is considered as one of the important milestones in girls treated for AN.Aim: To quantify the estro...

hrp0084p2-342 | Fat | ESPE2015

Changes in Insulin Sensitivity in Adolescents Who Underwent Bariatric Surgery: Effects of Laparoscopic Sleeve Gastrectomy and Laparoscopic Gastric Banding

De Filippo Gianpaolo , Pourcher Guillaume , Khen-Dunlop Naziha , Kyheng Christele , Dagher Ibrahim , Bougneres Pierre

Background: In adults, bariatric surgery has gradually emerged as a ‘metabolic’ surgery, able to rapidly improve metabolic disturbances linked to severe obesity. Even if type 2 diabetes is rare in european obese adolescents, alterations in insulin sensitivity are present in almost all.Objective and hypotheses: To evaluate the modification of insulin resistance (IR) and insulin sensitivity (IS) in severe obese adolescents who underwent bariatric...

hrp0084p3-842 | Fat | ESPE2015

Hepatic Steatosis Influences Significantly the Cardiovascular Risk in Children with Metabolic Syndrome

Rutigliano Irene , De Filippo Gianpaolo , Vinci Roberta , Kyheng Christele , Petraccaro Agostino , Conoscitore Michele , Pettoello-Mantovani Massimo , Campanozzi Angelo

Background: Despite the metabolic syndrome in pediatrics is a well recognized entity, there is no unanimous consensus on exact value of MS to predict long-term cardiovascular risk. Hepatic Steatosis (HS) is another emerging condition associated to pediatric obesity.Objective and hypotheses: To evaluate the prevalence of MS in a large pediatric obese population, assess the relationship between MS and HS, and evaluating the possible role of HS in defining ...